Genomics is a field of technology that changes at an alarmingly rapid rate. It’s difficult to find types of other fields which have undergone change at similar rates, but comparisons could include the evolution of computer technology in the last several decades or the rapid growth of Internet startups in the 90s. Unlike these examples, the growth of genome sequencing technology is limited by a certain technological sector, or at least, it’s been until now.
Sequencing technology has become passing a crucial point, where the cost of whole genome sequencing is really below the cost of managing a conventional panel of genetic tests. Though it is difficult to calculate a precise figure because of this, it probably is based on the range of $1K-$10K. Illumina’s HiSeq platform or IonTorrent’s Proton both promise Di truyền học genomic sequencing in this range, along with Complete Genomics. As we pass this time, genome sequencing moves from the realm of research technology to viable clinical diagnostic test.
The consequences of this change could be observed in the growing widespread curiosity about sequencing technology. While technologies of this type have revolutionized many areas of research in the last decade, their used in clinical settings has profound implications because of this industry. Research applications can only just provide a small source of profits. Moving into clinical applications provides use of a much bigger amount of capital, both due to the larger market and higher profit margins.
The clinical introduction of genome sequencing technology will change many facets of healthcare next few years. Genome sequencing could eventually take the spot of a regular section of a patient’s healthcare record, in quite similar way as blood type and allergies to medication are used today. However, we’ve a lot of ground to cover before we get to the point. For entrepreneurs in this field, this equates to a variety of exciting opportunities.
While interpretation of genomic has been an important part of research, the growing use of this data in clinical fields will generate a great demand for the unambiguous interpretation of results. Physicians want an unambiguous questions such as disease predisposition, and they’d like a trustworthy party to assume the responsibility for causeing the judgement. Recently, an increasing quantity of companies have entered the location of genomic data interpretation, many small startups such as Genformatic, a Bioinformatics company located in Austin. Larger companies also have begun to concentrate on providing these services. As this industry evolves, it is likely that more companies may enter this realm, and it will soon be interesting to observe how things develop in this area.
While anyone with experience in Molecular Biology possesses the necessary skills to organize and run libraries, a lot of things can fail in this process. Even in pure research applications, sample preparation can be an increasingly common service supplied by a variety of centers, along with boutique services, such as Genome Organizer’s ChIP-Seq service. It’s not too researchers can’t perform these tasks, however when they are available for a fee, they see little benefit to running these services for themselves. As genomic sequencing moves to the clinical realm, demand for such services can be likely to increase. You will find few hospitals with the present capability to perform basic sample preparation, and this represents a fresh part of opportunity in this field.
One of many greatest areas of uncertainty of this type today is how samples are certain to get from physicians’ offices to sequencing centers, and who’ll inform patients of their results. Though medical school curricula may 1 day include the interpretation of genomic data, we’re far from that point today. Currently, even the administration and interpretation of Genetic tests is generally left to individuals in the field of Genetic Counseling, in collaboration with statisticians and specialists. Though it is likely that a variety of other professionals will dominate the responsibility of this field in the future, it is likely that in the long run, the growth will take place in this field.